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Six COVID vaccine deals toward guaranteed supply

Canada has signed agreements with six companies: AstraZeneca, Sanofi & GlaxoSmithKline, Johnson & Johnson, Novavax, Pfizer, Moderna. Full payments to drug companies are contingent on the vaccines passing clinical trials and obtaining regulatory approval.

COVID-19, vaccine
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Friday September 25, 2020 | NATIONAL

by Mary P Brooke, B.Sc., Editor | Island Social Trends

As Canadians continue to deal with the health and economic impacts of the global pandemic, the Government of Canada is signing new agreements to establish a guaranteed supply of potential vaccines that will help keep Canadians safe and healthy.

Today Prime Minister Justin Trudeau held a press briefing accompanied by Chief Public Health Officer Dr Theresa Tam, announcing an agreement with AstraZeneca to procure up to 20 million doses of its COVID‑19 vaccine candidate.

Prime Minister Justin Trudeau announcing the latest COVID-19 vaccine procurement update, September 25, 2020 in Ottawa.

This agreement adds to those already reached with Sanofi and GlaxoSmithKline, Johnson & Johnson, Novavax, Pfizer, and Moderna, which were made following the recommendations of the COVID-19 Vaccine Task Force. With these agreements in place, the government has now secured access for Canadians to six leading vaccine candidates.

“The best way to end this pandemic, and to keep Canadians healthy, is with a safe and effective vaccine. By investing in multiple vaccine candidates and ensuring that we can distribute one quickly from coast to coast to coast, we are taking the necessary steps to put Canadians on the path to recovery from COVID-19,” said Trudeau.

Having Canadians’ backs:

Trudeau reiterated today in his live press briefing that “protecting people will continue to be ‘Job 1’ as we move forward”.

“One of the best ways to do that is with a safe and effective vaccine,” he said at the top of the noon hour announcement (9 am Pacific Time).

Advanced screening and support for vaccine research in clinical trials has already been invested in by the federal government, he said. “We have been guided by science since the very beginning,” Trudeau said.

“Both the COVID-19 Task Force and the Immunity Task Force are doing important work to help us identify the most promising vaccine options and strategies,” the prime minister said.

Trudeau’s thumbs up for Premier Horgan:

Premier John Horgan, Prime Minister Justin Trudeau, BC Transit
Premier John Horgan and Prime Minister Justin Trudeau delivering news together in Victoria last year (July 2019). [West Shore Voice News photo by Mary Brooke]

Today Trudeau distinctly acknowledged BC Premier John Horgan for his leadership with guiding premiers and the federal government in highlighting the importance of paid sick leave for people who are told or expected to stay away from work in self-isolation due to COVID-19 illness, symptoms, or known exposure.

The federal NDP under Jagmeet Singh’s leadership are holding firm for Canadians as well, by articulating what needed to be in the Liberal government’s promises (in the Throne Speech) going forward in the fall and winter amidst the pandemic. If the NDP support Liberal legislation now for adjustments to EI and the Recovery Benefit (a combo of programs to replace the expiring CERB program)

Canada helping globally:

GAVI, COVID-19
GAVI network for vaccine development and distribution.

Trudeau also announced Canada’s participation in the COVID-19 Vaccine Global Access (COVAX) Facility, a global procurement mechanism instigated by the Bill & Melinda Gates Foundation. The organization aims to help deliver fair, equitable, and timely access to COVID-19 vaccines.

“This pandemic can’t be solved by any one country alone, because to eliminate the virus anywhere we need to eliminate it everywhere,” Trudeau said today in new news conference, leading to an announcement of $440 million to the international co-initiative. This will help develop doses for Canadians and for people in developing countries.

About $220 million will procure up to 15 million vaccine doses for Canadians. The other $220 million will be channeled through the COVAX Advance Market Commitment to purchase doses for low- and middle-income countries.

By joining this initiative, Canada says it is helping to develop and deploy safe, effective, and accessible COVID-19 vaccines.

BC Health Minister, Adrian Dix, September 17, 2020
We’ll be living with COVID-19 pandemic conditions for years, said BC Health Minister Adrian Dix, September 17, 2020.

In BC over the past few months, a supportive philosophy has been espoused by Adrian Dix as Health Minister and Provincial Health Officer Dr Bonnie Henry, saying that so long as the COVID-19 is out there, it is potentially everywhere. This is especially important given that people travel and can bring the virus back home with them.

Dr Bonnie Henry, Provincial Health Officer
BC Provincial Health Officer Dr Bonnie Henry at her COVID press briefing on Thursday September 24, 2020 in Victoria.

“Protecting Canadians from COVID-19 is priority number one, and the first foundation of the Government of Canada’s plan for a stronger and more resilient Canada,” it was stated in a release today from the Prime Minister’s office. “Together, we will keep Canadians healthy and ensure they have the support they need, while we work toward beating this virus.”

Internal team approach:

Today and going forward, Trudeau will be giving most of his COVID-related messages accompanied by federal ministers.

Clinical trials: “The health and safety of Canadians is our government’s priority. We’re taking action on a comprehensive plan that includes investing in clinical trials, securing the supply of an eventual vaccine, and increasing Canada’s biomanufacturing capacity to ensure Canadians have access to a safe and effective vaccine for COVID-19.” ~ The Hon. Navdeep Bains, Minister of Innovation, Science and Industry

Various types of vaccines: “The Government of Canada continues to work diligently to protect the health and safety of Canadians during the pandemic. With today’s announcement, we have agreements in place that guarantee Canada access to multiple vaccine candidates of various types including viral vector, protein subunit, and mRNA. The diversity of our portfolio ensures that when these vaccines have been proven to be safe and effective, Canadians will have access to them.” ~ The Hon. Anita Anand, Minister of Public Services and Procurement

Coordinated action: “The COVID-19 pandemic will only be overcome through coordinated action around the world. We strongly believe that supporting other countries in their fight against COVID-19 is crucial to protect Canadians at home. Canada is committed to supporting the COVAX Facility, and the Advance Market Commitment within it, to ensure all participating countries have rapid, fair, and equitable access to COVID-19 vaccines. The Facility is an example of how multilateral cooperation can allow us to accomplish together what none of us could accomplish alone.” ~ The Hon. Karina Gould, Minister of International Development

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Vaccine types & contracts:

Disabling or eradicating the COVID-19 virus – approaches include viral vector, protein subunit, and mRNA.
  • The Government of Canada has signed agreements with the following companies:
    • AstraZeneca, which will supply up to 20 million doses of its viral vector vaccine candidate AZD1222.
    • Sanofi and GlaxoSmithKline, which will supply up to 72 million of doses of their protein subunit vaccine candidate.
    • Johnson & Johnson, which will supply up to 38 million doses of its viral vector vaccine candidate Ad26.COV2.S.
    • Novavax, which will supply up to 76 million doses of its protein subunit vaccine candidate NVX-CoV2373.
    • Pfizer, which will supply a minimum of 20 million doses of its mRNA vaccine candidate, BNT162. The government is negotiating with the company to expand the agreement to include options for obtaining additional doses.
    • Moderna, which will supply up to 56 million doses of its mRNA vaccine candidate mRNA-1273.
  • Currently, no vaccines have been approved to prevent COVID-19 infection in Canada. Many vaccines are in clinical trials or under development. Once additional studies have been completed, Health Canada will review the evidence of safety, efficacy, and manufacturing quality for each vaccine to determine whether individual vaccines will be approved for use in Canada, before they are made available to Canadians.
  • Full payments to drug companies are contingent on the vaccines passing clinical trials and obtaining regulatory approval. All contracts the Government of Canada signs with vaccine developers contain off-ramps and exit provisions, should they be required.
  • The Government of Canada is also securing the equipment and supplies needed for the final phases of vaccine manufacturing and packaging in Canada as well as the equipment required for safe and effective immunization, including syringes, needles, and alcohol swabs.
  • The COVAX Facility is managed by Gavi, the Vaccine Alliance, in close partnership with the Coalition for Epidemic Preparedness Innovations and the World Health Organization.
  • The COVAX Facility is currently investing in vaccine production capacity across multiple vaccine candidates so that, upon regulatory approval, doses can be made available to participants.
  • Canada’s commitment to the COVAX Facility complements its bilateral agreements with vaccine manufacturers and further diversifies Canada’s portfolio of vaccine candidates.
  • The $440 million in funding announced today is in addition to the up to $25 million (USD) the Government of Canada committed to the COVAX Advance Market Commitment in July 2020.  

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